COPS5 Antibody

Size : 50 µL Clone Number: Aliases: 38 kDa Mov34 homolog antibody; COP9 (constitutive photomorphogenic) homolog subunit 5 antibody; COP9 constitutive photomorphogenic homolog subunit 5 antibody; COP9 signalosome complex subunit 5 antibody; COP9 signalosome subunit 5 antibody; Cop9 subunit 5 antibody; COPS 5 antibody; cops5 antibody; CSN 5 antibody; CSN5 antibody; CSN5_HUMAN antibody; JAB 1 antibody; Jun activation domain binding protein 1 antibody; Jun activation domain binding protein antibody; Jun activation domain-binding protein 1 antibody; MGC3149 antibody; MOV 34 antibody; MOV34 antibody; MOV34 family; 38-KD member antibody; SGN 5 antibody; SGN5 antibody; Signalosome subunit 5 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q92905 Immunogen: Fusion protein of Human COPS5 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 10000, WB: 1: 1000-1: 5000, IHC: 1: 150-1: 500 Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: COPS5 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology