CAPRIN2 Antibody, HRP conjugated

Size : 50 µL Clone Number: Aliases: C1q domain-containing protein 1 antibody; C1QDC1 antibody; CAPR2_HUMAN antibody; Caprin family member 2 antibody; Caprin-2 antibody; caprin2 antibody; Cytoplasmic activation/proliferation-associated protein 2 antibody; EEG 1 antibody; EEG1 antibody; Gastric cancer multidrug resistance-associated protein antibody; KIAA1873 antibody; Protein EEG-1 antibody; RNA granule protein 140 antibody; RNG140 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q6IMN6 Immunogen: Peptide sequence from Human Caprin-2 protein (83-100AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (PubMed: 18762581). Faciliates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling (PubMed: 27821587). May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation (PubMed: 14593112). May be involved in apoptosis (PubMed: 14593112). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: HRP Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAPRIN2 Research Areas: Cell biology; Stem cells