C2CD3 Antibody

Size : 50 µg Clone Number: Aliases: C2CD3 antibody; C2 domain-containing protein 3 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q4AC94 Immunogen: Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC: 1: 20-1: 200, IF: 1: 50-1: 200 Background: Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed: 24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed: 23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: C2CD3 Research Areas: Others