CENPF Antibody

Size : 50 µL Clone Number: Aliases: AH antigen antibody; Cell cycle dependent 350K nuclear protein antibody; CENF antibody; CENP F antibody; CENP F kinetochore protein antibody; CENP-F antibody; CENPF antibody; CENPF kinetochore protein antibody; CENPF_HUMAN antibody; Centromere protein F 350/400ka antibody; Centromere protein F antibody; Centromere protein F, 350/400kDa antibody; CILD31 antibody; Hcp 1 antibody; Hcp1 antibody; Kinetochore protein CENP F antibody; Kinetochore protein CENPF antibody; Mitosin antibody; PRO1779 antibody; STROMS antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P49454 Immunogen: Synthetic peptide of Human CENPF Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CENPF Research Areas: Epigenetics and Nuclear Signaling