CNTN1 Antibody, HRP conjugated

Size : 50 µg Clone Number: Aliases: CNTN 1 antibody; CNTN antibody; Cntn1 antibody; CNTN1_HUMAN antibody; Contactin-1 antibody; Contactin1 antibody; F3 antibody; F3cam antibody; Glycoprotein gp135 antibody; gp 135 antibody; GP135 antibody; MYPCN antibody; Neural cell surface protein F3 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q12860 Immunogen: Recombinant Human Contactin-1 protein (686-866AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: HRP Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CNTN1 Research Areas: Neuroscience