CDC42 Antibody

Size : 50 µL Clone Number: Aliases: CDC42 antibody; CDC42_HUMAN antibody; CDC42Hs antibody; Cell division control protein 42 homolog antibody; Cell division cycle 42 (GTP binding protein 25kDa) antibody; Cell division cycle 42 antibody; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein; 25kD)) antibody; dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein; 25kD)) antibody; G25K antibody; G25K GTP-binding protein antibody; Growth regulating protein antibody; GTP binding protein 25kDa antibody; Small GTP binding protein CDC42 antibody; TKS antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P60953 Immunogen: Synthetic peptide of Human CDC42/RHO/RAC Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000 Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDC42 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Signal transduction