CHAF1A Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: CAF 1 antibody; CAF 1 subunit A antibody; CAF antibody; CAF I 150 kDa subunit antibody; CAF I p150 antibody; CAF-1 subunit A antibody; CAF-I 150 kDa subunit antibody; CAF-I p150 antibody; CAF1 antibody; CAF1A_HUMAN antibody; CAF1B antibody; CAF1P150 antibody; CHAF1A antibody; Chromatin assembly factor 1 subunit A antibody; Chromatin Assembly Factor 1 Subunit A p150 antibody; Chromatin assembly factor I (150 kDa) antibody; Chromatin assembly factor I 150 kDa antibody; Chromatin assembly factor I p150 subunit antibody; DCAF1 antibody; hp150 antibody; MGC71229 antibody; P150 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q13111 Immunogen: Recombinant Human Chromatin assembly factor 1 subunit A protein (840-904AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHAF1A Research Areas: Epigenetics and Nuclear Signaling