CKAP5 Antibody, HRP conjugated

Size : 50 µg Clone Number: Aliases: CKAP5 antibody; KIAA0097Cytoskeleton-associated protein 5 antibody; Colonic and hepatic tumor overexpressed gene protein antibody; Ch-TOG antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q14008 Immunogen: Recombinant Human Cytoskeleton-associated protein 5 protein (1802-2019AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed: 23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed: 27156448). Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: HRP Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CKAP5 Research Areas: Cancer; Cell biology; Tags & Cell Markers; Signal transduction