CNGA3 Antibody

Size : 50 µL Clone Number: Aliases: ACHM2 antibody; CCNC1 antibody; CCNCa antibody; CCNCalpha antibody; CNCG3 antibody; CNG 3 antibody; CNG channel alpha 3 antibody; CNG channel alpha-3 antibody; CNG-3 antibody; CNG3 antibody; CNGA3 antibody; Cnga3 cyclic nucleotide gated channel alpha 3 antibody; CNGA3_HUMAN antibody; Cone photoreceptor cGMP gated channel antibody; Cone photoreceptor cGMP gated channel alpha subunit antibody; Cone photoreceptor cGMP gated channel subunit alpha antibody; Cone photoreceptor cGMP-gated channel subunit alpha antibody; Cyclic nucleotide gated cation channel alpha 3 antibody; Cyclic nucleotide gated channel alpha 3 antibody; Cyclic nucleotide gated channel olfactory 3 antibody; Cyclic nucleotide gated channel rod photoreceptor subunit alpha antibody; Cyclic nucleotide-gated cation channel alpha-3 antibody; Cyclic nucleotide-gated channel alpha-3 antibody; OTTHUMP00000161120 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q16281 Immunogen: Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CNGA3 Research Areas: Neuroscience