CAST Antibody

Size : 50 µL Clone Number: Aliases: BS 17 antibody; Calpain inhibitor antibody; Calpastatin antibody; Cast antibody; Heart type calpastatin antibody; ICAL_HUMAN antibody; MGC9402 antibody; Sperm BS 17 component antibody; Sperm BS-17 component antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P20810 Immunogen: Fusion protein of Human CAST Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 100-1: 300 Background: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAST Research Areas: Neuroscience;Cell biology