CST3 Antibody

Size : 50 µL Clone Number: Aliases: AD 8 antibody; AD8 antibody; Amyloid angiopathy and cerebral hemorrhage antibody; ARMD11 antibody; bA218C14.4 (cystatin C) antibody; bA218C14.4 antibody; Cst 3 antibody; Cst3 antibody; CST3 protein antibody; Cystatin 3 antibody; Cystatin-3 antibody; Cystatin-C antibody; Cystatin3 antibody; CystatinC antibody; CYTC_HUMAN antibody; Epididymis secretory protein Li 2 antibody; Gamma trace antibody; Gamma-trace antibody; HCCAA antibody; HEL S 2 antibody; MGC117328 antibody; Neuroendocrine basic polypeptide antibody; Post gamma globulin antibody; Post-gamma-globulin antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P01034 Immunogen: Synthetic peptide of Human CST3 Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 10000, WB: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CST3 Research Areas: Cardiovascular?Cell biology;Tags & Cell Markers;Stem cells