CLPS Antibody

Size : 50 µL Clone Number: Aliases: clpS antibody; COL_HUMAN antibody; Colipase antibody; Colipase pancreatic antibody; Pancreatic colipase preproprotein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P04118 Immunogen: Fusion protein of Human CLPS Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 50-1: 200 Background: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLPS Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction