BAIAP2 Antibody

Size : 50 µL Clone Number: Aliases: BAI-associated protein 2 antibody; BAI1 associated protein 2 antibody; BAI1-associated protein 2 antibody; BAIAP 2 antibody; Baiap2 antibody; BAIP2_HUMAN antibody; BAP2 antibody; Brain-specific angiogenesis inhibitor 1-associated protein 2 antibody; Fas ligand-associated factor 3 antibody; FLAF3 antibody; Insulin receptor substrate p53 antibody; Insulin receptor substrate p53/p58 antibody; Insulin receptor substrate protein of 53 kDa antibody; IRS-58 antibody; IRSp53 antibody; IRSp53/58 antibody; Protein BAP2 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UQB8 Immunogen: Fusion protein of Human BAIAP2 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 50-1: 200 Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: BAIAP2 Research Areas: Neuroscience