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CARD6 Antibody

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Size : 100 µL Clone Number: Aliases: Caspase recruitment domain-containing protein 6; CARD6; Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q52LR2 Immunogen: Synthesized peptide derived from Human CARD6. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC, IF; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100, IF: 1: 100-1: 500 Background: This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646. Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806. Vassiliki Poulaki, Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 358 - 366. Lucia Ricci-Vitiani, J. Exp. Med., Nov 2004; 200: 1257 - 1266. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CARD6 Research Areas: Others

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