CLDN10 Antibody

Size : 100 µL Clone Number: Aliases: Claudin-10 antibody; Claudin10 antibody; CLD10_HUMAN antibody; CLDN 10 antibody; CLDN10 antibody; CLDN10 protein antibody; CPETRL 3 antibody; CPETRL3 antibody; HGNC: 2033 antibody; OSP L antibody; OSP like protein antibody; OSP-like protein antibody; OSPL antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P78369 Immunogen: Synthesized peptide derived from Human Claudin 10. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney. Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 - 556. Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 - 944. Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 - F1299. Anne Florin, Endocrinology, Mar 2005; 146: 153 Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLDN10 Research Areas: Signal transduction