CCP110 Antibody

Size : 50 µL Clone Number: Aliases: 110 kDa centrosomal protein antibody; CCP110 antibody; Centriolar coiled coil protein 110kDa antibody; Centrosomal protein 110 kDa antibody; Centrosomal protein CP110 antibody; Centrosomal protein of 110 kDa antibody; Cep110 antibody; CP110 antibody; CP110_HUMAN antibody; DKFZp781G1416 antibody; FAN antibody; KIAA0419 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O43303 Immunogen: Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed: 17719545 PubMed: 17681131, PubMed: 23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed: 16760425). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCP110 Research Areas: Cancer; Cell biology; Tags & Cell Markers