CASP7 Antibody

Size : 50 µL Clone Number: Aliases: apoptosis-related cysteine peptidase antibody; Apoptotic protease Mch-3 antibody; CASP-7 antibody; CASP7 antibody; CASP7_HUMAN antibody; Caspase-7 subunit p11 antibody; CMH-1 antibody; ICE-LAP3 antibody; ICE-like apoptotic protease 3 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P55210 Immunogen: Fusion protein of Human CASP7 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000, IHC: 1: 25-1: 100 Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CASP7 Research Areas: Cancer;Cell biology;Metabolism