CYP1A2 Antibody

Size : 50 µL Clone Number: Aliases: Aryl hydrocarbon hydroxylase antibody; CP 12 antibody; CP12 antibody; CP1A2_HUMAN antibody; CYP1A2 antibody; CYPIA2 antibody; Cytochrome P(3)450 antibody; Cytochrome P450 1A2 antibody; Cytochrome P450 4 antibody; Cytochrome P450 family 1 polypeptide 2 antibody; Cytochrome P450 family 1 subfamily A polypeptide 2 antibody; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2 antibody; Cytochrome P450-P3 antibody; Cytochrome P4501A2 antibody; Dioxin inducable P3 450 antibody; Flavoprotein linked monooxygenase antibody; Flavoprotein-linked monooxygenase antibody; Microsomal monooxygenase antibody; P(3)450 antibody; P3 450 antibody; P450 4 antibody; P450 form 4 antibody; P450 P3 antibody; P450(PA) antibody; Xenobiotic monooxygenase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P05177 Immunogen: Synthetic peptide of Human CYP1A2 Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 50-1: 200 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP1A2 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction