AD7C-NTP Antibody

Size : 50 µL Clone Number: Aliases: Neuronal thread protein AD7c-NTP Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Immunogen: Synthetic peptide of Human AD7C-NTP Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 25-1: 100 Background: The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: Research Areas: Others