CYP2B6 Antibody

Size : 50 µL Clone Number: Aliases: 1,4 cineole 2 exo monooxygenase antibody; 11B1 antibody; CP2B6_HUMAN antibody; CPB 6 antibody; CPB6 antibody; CYP 2B6 antibody; CYP IIB6 antibody; CYP2B antibody; CYP2B6 antibody; CYP2B7 antibody; CYP2B7P antibody; CYPIIB6 antibody; Cytochrome P450 2B6 antibody; Cytochrome P450 family 2 subfamily B antibody; Cytochrome P450 family 2 subfamily B polypeptide 6 antibody; Cytochrome P450 IIB1 antibody; Cytochrome P450 phenobarbital inducible antibody; Cytochrome P450 subfamily IIB (phenobarbital inducible) antibody; Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6 antibody; Cytochrome P450 subfamily IIB polypeptide 6 antibody; EFVM antibody; IIB1 antibody; P450 antibody; P450 IIB1 antibody; P450IIB1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P20813 Immunogen: Synthetic peptide of Human CYP2B6 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 50-1: 200 Background: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP2B6 Research Areas: Cardiovascular;Metabolism;Signal transduction