COX11 Antibody

Size : 50 µL Clone Number: Aliases: COX11 antibody; COX11 homolog antibody; COX11 homolog; cytochrome c oxidase assembly protein (yeast) antibody; COX11_HUMAN antibody; COX11P antibody; Cytochrome c oxidase assembly protein COX11 antibody; Cytochrome c oxidase assembly protein COX11; mitochondrial antibody; Cytochrome c oxidase subunit 11 antibody; mitochondrial antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y6N1 Immunogen: Fusion protein of Human COX11 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 10000, WB: 1: 1000-1: 5000, IHC: 1: 25-1: 100 Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: COX11 Research Areas: Others