CLDND1 Antibody

Size : 50 µL Clone Number: Aliases: CLDND1 antibody; C3orf4 antibody; HSPC174 antibody; PSEC0054 antibody; UNQ2511/PRO6000Claudin domain-containing protein 1 antibody; Membrane protein GENX-3745 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9NY35 Immunogen: Fusion protein of Human CLDND1 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 50-1: 200 Background: CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLDND1 Research Areas: Neuroscience;Cell biology