CNGA1 Antibody

Size : 100 µL Clone Number: Aliases: cGMP gated cation channel alpha 1 antibody; cGMP-gated cation channel alpha-1 antibody; CNCG antibody; CNCG1 antibody; CNG 1 antibody; CNG channel alpha 1 antibody; CNG channel alpha-1 antibody; CNG-1 antibody; CNG1 antibody; Cnga1 antibody; CNGA1_HUMAN antibody; Cyclic nucleotide gated cation channel 1 antibody; Cyclic nucleotide gated channel alpha 1 antibody; Cyclic nucleotide gated channel photoreceptor antibody; Cyclic nucleotide-gated cation channel 1 antibody; Cyclic nucleotide-gated channel alpha-1 antibody; Cyclic nucleotide-gated channel antibody; Interleukin 1 homologue antibody; OTTHUMP00000218675 antibody; OTTHUMP00000223313 antibody; OTTHUMP00000223314 antibody; photoreceptor antibody; RCNC1 antibody; RCNCa antibody; RCNCalpha antibody; Rod photoreceptor cGMP gated channel subunit alpha antibody; Rod photoreceptor cGMP-gated channel subunit alpha antibody; RP49 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P29973 Immunogen: Synthesized peptide derived from internal of Human CNGA1. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Pittler S.J., J. Biol. Chem. 267: 6257-6262(1992). Dhallan R.S., J. Neurosci. 12: 3248-3256(1992). Ota T., Nat. Genet. 36: 40-45(2004). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CNGA1 Research Areas: Neuroscience;Signal transduction