CRTAM Antibody

Size : 50 µL Clone Number: Aliases: CD355 antibody; Class I MHC restricted T cell associated molecule antibody; Class-I MHC-restricted T-cell-associated molecule antibody; CRTAM antibody; CRTAM_HUMAN antibody; Cytotoxic and regulatory T cell molecule antibody; Cytotoxic and regulatory T-cell molecule antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O95727 Immunogen: Fusion protein of Human CRTAM Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CRTAM Research Areas: Immunology