CYP3A4 Antibody

Size : 100 µL Clone Number: Aliases: 1,8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CP33 antibody; CP34 antibody; CP3A4_HUMAN antibody; CYP3 antibody; CYP3A antibody; CYP3A3 antibody; CYP3A4 antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 3A4 antibody; Cytochrome P450 family 3 subfamily A polypeptide 4 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450 subfamily IIIA polypeptide 4 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody; Cytochrome P450-PCN1 antibody; Glucocorticoid inducible P450 antibody; HLP antibody; MGC126680 antibody; NF 25 antibody; NF25 antibody; Nifedipine oxidase antibody; P450 III steroid inducible antibody; P450 PCN1 antibody; P450, family III antibody; P450C3 antibody; P450PCN1 antibody; Quinine 3 monooxygenase antibody; Quinine 3-monooxygenase antibody; Taurochenodeoxycholate 6 alpha hydroxylase antibody; Taurochenodeoxycholate 6-alpha-hydroxylase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P08684 Immunogen: Synthesized peptide derived from internal of Human Cytochrome P450 3A4. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide. Vuoristo M.M., J. Biol. Chem. 270: 22873-22881(1995). Mungall A.J., Nature 425: 805-811(2003). Lui V.C., Genomics 32: 401-412(1996). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP3A4 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction