CLDN11 Antibody

Size : 50 µL Clone Number: Aliases: Claudin 11 antibody; Claudin-11 antibody; CLD11_HUMAN antibody; Cldn11 antibody; Oligodendrocyte transmembrane protein antibody; Oligodendrocyte-specific protein antibody; OSP antibody; OTM antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O75508 Immunogen: Synthetic peptide of Human CLDN11 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 2000, IHC: 1: 25-1: 100 Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLDN11 Research Areas: Neuroscience;Immunology