CTLA4 Antibody

Size : 100 µL Clone Number: Aliases: ALPS5 antibody; CD 152 antibody; CD antibody; CD152 antibody; CD152 antigen antibody; CD152 isoform antibody; Celiac disease 3 antibody; CELIAC3 antibody; CTLA 4 antibody; CTLA-4 antibody; CTLA4 antibody; CTLA4_HUMAN antibody; Cytotoxic T cell associated 4 antibody; Cytotoxic T lymphocyte antigen 4 antibody; Cytotoxic T lymphocyte associated 4 antibody; Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody; Cytotoxic T lymphocyte associated antigen 4 antibody; Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody; Cytotoxic T lymphocyte associated protein 4 antibody; Cytotoxic T lymphocyte associated serine esterase 4 antibody; Cytotoxic T lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte-associated antigen 4 antibody; GRD4 antibody; GSE antibody; ICOS antibody; IDDM12 antibody; insulin-dependent diabetes mellitus 12 antibody; Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody; OTTHUMP00000216623 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P16410 Immunogen: Synthetic peptide corresponding to residues near the C terminal of Human Cytotoxic T-lymphocyte protein 4 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTLA4 Research Areas: Immunology;Stem cells