BRK1 Antibody

Size : 50 µL Clone Number: Aliases: BRK1 antibody; C3orf10 antibody; HSPC300 antibody; MDS027 antibody; Protein BRICK1 antibody; BRK1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q8WUW1 Immunogen: Synthetic peptide of Human BRK1 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 50-1: 200 Background: HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: BRK1 Research Areas: Signal transduction