CDKN1C Antibody

Size : 50 µL Clone Number: Aliases: Beckwith Wiedemann syndrome antibody; BWCR antibody; BWS antibody; CDKI antibody; CDKN 1C antibody; CDKN1C antibody; CDN1C_HUMAN antibody; Cyclin dependent kinase inhibitor 1C antibody; Cyclin dependent kinase inhibitor p57 antibody; Cyclin-dependent kinase inhibitor 1C antibody; Cyclin-dependent kinase inhibitor p57 antibody; KIP 2 antibody; KIP2 antibody; p57 antibody; p57 Kip 2 antibody; p57KIP2 antibody; WBS antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P49918 Immunogen: Synthetic peptide of Human CDKN1C Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 25-1: 100 Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CDKN1C Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology