CYP2E1 Antibody

Size : 50 µL Clone Number: Aliases: 4-nitrophenol 2-hydroxylase antibody; CP2E1_HUMAN antibody; CPE1 antibody; CYP2E antibody; Cyp2e1 antibody; CYPIIE1 antibody; Cytochrome P450 2E1 antibody; Cytochrome P450 isozyme 3A antibody; Cytochrome P450 LM3A antibody; Cytochrome P450; family 2; subfamily e; polypeptide 1 antibody; cytochrome P450; subfamily IIE (ethanol-inducible); polypeptide 1 antibody; Cytochrome P450; subfamily IIE antibody; Cytochrome P450-ALC antibody; Cytochrome P450-J antibody; Cytochrome P450RLM6 antibody; EC 1.14.13.- antibody; EC 1.14.13.n7 antibody; Ethanol-inducible P450 antibody; Flavoprotein-linked monooxygenase antibody; MGC133529 antibody; Microsomal monooxygenase antibody; OTTHUMP00000020813 antibody; OTTHUMP00000046571 antibody; P450 ALC antibody; P450-J antibody; P450C2E antibody; P450J antibody; P450RLM6 antibody; Xenobiotic monooxygenase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P05181 Immunogen: Fusion protein of Human CYP2E1 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 2000, WB: 1: 500-1: 2000, IHC: 1: 25-1: 100 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP2E1 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction