CAMK2G/CAMK2B Antibody

Size : 100 µL Clone Number: Aliases: Calcium/calmodulin-dependent protein kinase type II gamma chain; EC 2.7.11.17; CaM-kinase II gamma chain; CaM kinase II subunit gamma; CaMK-II subunit gamma Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q13555/Q13554 Immunogen: Synthesized peptide derived from C-terminal of Human CaMK2?/γ. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.Deloukas P., Nature 429: 375-381(2004).Breen M.A., Biochem. Biophys. Res. Commun. 236: 473-478(1997).Tombes R.M., Biochim. Biophys. Acta 1355: 281-292(1997). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAMK2G/CAMK2B Research Areas: Neuroscience;Signal transduction