CHST2 Antibody

Size : 100 µL Clone Number: Aliases: CHST2 antibody; GN6STCarbohydrate sulfotransferase 2 antibody; EC 2.8.2.- antibody; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2 antibody; GST-2 antibody; N-acetylglucosamine 6-O-sulfotransferase 1 antibody; GlcNAc6ST-1 antibody; Gn6ST-1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y4C5 Immunogen: Synthesized peptide derived from internal of Human CHST2. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains. Uchimura K., J. Biochem. 124: 670-678(1998). Li X., Genomics 55: 345-347(1999). Sakaguchi H., Biochim. Biophys. Acta 1523: 269-276(2000). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHST2 Research Areas: Tags & Cell Markers