CUEDC2 Antibody
Size : 100 µL
Clone Number:
Aliases: bA18I14.5 antibody; C10orf66 antibody; Chromosome 10 open reading frame 66 antibody; CUE domain containing 2 antibody; CUE domain-containing protein 2 antibody; CUED2 antibody; CUED2_HUMAN antibody; Cuedc2 antibody; MGC2491 antibody; OTTHUMP00000020368 antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q9H467
Immunogen: Peptide sequence around aa.262~266(D-V-R-N-P) derived from Human CUEDC2.
Host: Rabbit
Reactivity: Human, Mouse
Tested Applications: ELISA, WB; WB: 1: 500-1: 1000
Background:
Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
Zhang P.-J., Zhao J., Li H.-Y. EMBO J. 26: 1831-1842(2007)
Clonality: Polyclonal
Isotype: IgG
Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conjugate: Non-conjugated
Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: CUEDC2
Research Areas: Epigenetics and Nuclear Signaling;Signal transduction
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Internal Reference:
CSB-PA140363
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