CRKL Antibody

Size : 50 µL Clone Number: Aliases: Crk L antibody; Crk like protein antibody; Crk-like protein antibody; Crkl antibody; CRKL_HUMAN antibody; Crkol antibody; HGNC: 2363 antibody; Oncogene CrkL antibody; V crk avian sarcoma virus CT10 oncogene homolog like antibody; v crk sarcoma virus CT10 oncogene homolog (avian) like antibody; V crk sarcoma virus CT10 oncogene homolog avian like antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P46109 Immunogen: Synthetic peptide of Human CRKL Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 25-1: 100 Background: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CRKL Research Areas: Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Signal transduction