CLK4 Antibody

Size : 100 µL Clone Number: Aliases: AI987988 antibody; C85119 antibody; CDC like kinase 4 antibody; CDC-like kinase 4 antibody; CLK4 antibody; CLK4_HUMAN antibody; DKFZp686A20267 antibody; Dual specificity protein kinase CLK4 antibody; OTTMUSP00000005756; antibody; OTTMUSP00000005757 antibody; OTTMUSP00000041113 antibody; Protein serine threonine kinase Clk4 antibody; RP23-9N7.1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9HAZ1 Immunogen: Synthesized peptide derived from internal of Human CLK4. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; WB: 1: 500-1: 3000 Background: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Schultz J., Genomics 71: 368-370(2001). McNally T., Protein Sci. 12: 1562-1566(2003). Kantham L., Biochem. Biophys. Res. Commun. 304: 125-129(2003). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLK4 Research Areas: Epigenetics and Nuclear Signaling;Signal transduction