COQ3 Antibody

Size : 50 µL Clone Number: Aliases: COQ3 antibody; UG0215E05Ubiquinone biosynthesis O-methyltransferase antibody; mitochondrial antibody; 3-demethylubiquinol 3-O-methyltransferase antibody; EC 2.1.1.64 antibody; Polyprenyldihydroxybenzoate methyltransferase antibody; EC 2.1.1.114 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9NZJ6 Immunogen: Fusion protein of Human EIF2AK3 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 50-1: 200 Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: COQ3 Research Areas: Cancer;Tags & Cell Markers;Metabolism;Signal transduction