CDCA2 Antibody
Size : 100 µL
Clone Number:
Aliases: CDCA2Cell division cycle-associated protein 2 antibody; Recruits PP1 onto mitotic chromatin at anaphase protein antibody; Repo-Man antibody
Product Type: Polyclonal Antibody
Immunogen Species: Homo sapiens (Human)
UniProt ID: Q69YH5
Immunogen: Synthesized peptide derived from C-terminal of Human CDCA2.
Host: Rabbit
Reactivity: Human
Tested Applications: ELISA, WB; WB: 1: 500-1: 3000
Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
Walker M.G., Curr. Cancer Drug Targets 1: 73-83(2001).
Ota T., . Genet. 36: 40-45(2004).
Olsen J.V., Cell 127: 635-648(2006).
Clonality: Polyclonal
Isotype: IgG
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate: Non-conjugated
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names: CDCA2
Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism
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Internal Reference:
CSB-PA124174
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