CCDC88A Antibody

Size : 50 µL Clone Number: Aliases: AKT iphosphorylation enhancer antibody; Akt phosphorylation enhancer antibody; APE antibody; Ccdc88a antibody; Coiled coil domain containing 88A antibody; Coiled coil domain containing protein 88A antibody; Coiled-coil domain-containing protein 88A antibody; FLJ10392 antibody; G alpha interacting vesicle associated protein antibody; G alpha-interacting vesicle-associated protein antibody; Galpha interacting vesicle associated protein antibody; Girders of actin filament antibody; Girdin antibody; GIV antibody; GRDN antibody; GRDN_HUMAN antibody; HkRP1 antibody; Hook related protein 1 antibody; Hook-related protein 1 antibody; KIAA1212 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q3V6T2 Immunogen: Synthetic peptide of Human CCDC88A Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 5000, IHC: 1: 50-1: 200 Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCDC88A Research Areas: Neuroscience;Signal transduction