CLASP1 Antibody

Size : 100 µL Clone Number: Aliases: 1700030C23Rik antibody; 5730583A19Rik antibody; B130045P17Rik antibody; CLAP1_HUMAN antibody; clasp1 antibody; CLIP associating protein 1 antibody; CLIP associating protein CLASP1 antibody; CLIP-associating protein 1 antibody; Cytoplasmic linker associated protein 1 antibody; Cytoplasmic linker-associated protein 1 antibody; DKFZp686D1968 antibody; DKFZp686H2039 antibody; FLJ33821 antibody; FLJ41222 antibody; hOrbit1 antibody; KIAA0622 antibody; MAST1 antibody; MGC131895 antibody; mKIAA0622 antibody; Multiple asters 1 antibody; Multiple asters homolog 1 antibody; Protein Orbit homolog 1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q7Z460 Immunogen: Synthesized peptide derived from internal of Human CLASP1. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Maiato H., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 434: 724-731(2005). Akhmanova A., Cell 104: 923-935(2001). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLASP1 Research Areas: Cell biology