CARD8 Antibody

Size : 50 µL Clone Number: Aliases: Apoptotic protein NDPP 1 antibody; Apoptotic protein NDPP1 antibody; CARD 8 antibody; CARD inhibitor of NF kappa B activating ligand antibody; CARD inhibitor of NF kappaB activating ligand antibody; CARD inhibitor of NF kappaB activating ligands antibody; CARD-inhibitor of NF-kappa-B-activating ligand antibody; CARD8 antibody; CARD8_HUMAN antibody; CARDINAL antibody; Caspase recruitment domain containing protein 8 antibody; Caspase recruitment domain family member 8 antibody; Caspase recruitment domain protein 8 antibody; Caspase recruitment domain-containing protein 8 antibody; DACAR antibody; Dakar antibody; DKFZp779L0366 antibody; FLJ18119 antibody; FLJ18121 antibody; KIAA0955 antibody; MGC57162 antibody; NDPP 1 antibody; NDPP antibody; NDPP1 antibody; TUCAN antibody; Tumor up regulated CARD containing antagonist of CASP9 antibody; Tumor up regulated CARD containing antagonist of caspase 9 antibody; Tumor up-regulated CARD-containing antagonist of CASP9 antibody; tumor up-regulated CARD-containing antagonist of caspase nine antibody; Tumor upregulated CARD containing antagonist of CASP9 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y2G2 Immunogen: Fusion protein of Human CARD8 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 1000-1: 2000, IHC: 1: 25-1: 100 Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CARD8 Research Areas: Cell biology