BAG4 Antibody

Size : 50 µL Clone Number: Aliases: BAG 4 antibody; BAG family molecular chaperone regulator 4 antibody; BAG-4 antibody; BAG4 antibody; BAG4_HUMAN antibody; Bcl 2 associated athanogene 4 antibody; Bcl-2-associated athanogene 4 antibody; BCL2 associated athanogene 4 antibody; Silencer of death domains antibody; SODD antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O95429 Immunogen: Synthetic peptide of Human BAG4 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000 Background: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: BAG4 Research Areas: Cancer;Cell biology