CLIC4 Antibody

Size : 100 µL Clone Number: Aliases: Chloride intracellular channel 4 antibody; Chloride intracellular channel 4 (mitochondrial) antibody; Chloride intracellular channel 4 like antibody; Chloride intracellular channel protein 4 antibody; Clic4 antibody; CLIC4_HUMAN antibody; CLIC4L antibody; DKFZP566G223 antibody; FLJ38640 antibody; H1 antibody; HUH1 antibody; Intracellular chloride ion channel protein p64H1 antibody; MC3S5 antibody; mtCLIC antibody; p64H1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y696 Immunogen: Synthesized peptide derived from N-terminal of Human CLIC4. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). Wiemann S., Genome Res. 11: 422-435(2001). Edwards J.C.; Am. J. Physiol. 276: F398-F408(1999). Chuang J.Z., J. Neurosci. 19: 2919-2928(1999). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLIC4 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism;Signal transduction