CAV3 Antibody

Size : 50 µL Clone Number: Aliases: CAV3 antibody; CAV3_HUMAN antibody; Caveolin 3 antibody; Caveolin-3 antibody; LGMD1C antibody; LQT9 antibody; M-caveolin antibody; MGC126100 antibody; MGC126101 antibody; MGC126129 antibody; OTTHUMP00000115603 antibody; OTTHUMP00000207105 antibody; VIP 21 antibody; VIP21 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P56539 Immunogen: Synthetic peptide of Human CAV3 Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 50-1: 200 Background: This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAV3 Research Areas: Cardiovascular;Developmental biology?Tags & Cell Markers;Metabolism;Signal transduction