CERS4 Antibody

Size : 50 µL Clone Number: Aliases: ceramide synthase 4 antibody; CerS4 antibody; FLJ12089 antibody; LAG1 homolog ceramide synthase 4 antibody; LAG1 longevity assurance homolog 4 antibody; LAG1, S. cerevisiae, homolog of, 4 antibody; LASS 4 antibody; LASS4 antibody; LASS4 LAG1 homolog ceramide synthase 4 antibody; LASS4_HUMAN antibody; TRAM homolog 1 antibody; Trh 1 antibody; Trh1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9HA82 Immunogen: Synthetic peptide of Human CERS4 Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 50-1: 200 Background: The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22: 0- and C24: 0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CERS4 Research Areas: Cancer;Metabolism;Signal transduction