CATSPER3 Antibody

Size : 50 µL Clone Number: Aliases: Ca(v)-like protein antibody; CACRC antibody; calcium channel repeat containing 1 antibody; Cation channel sperm-associated protein 3 antibody; Cation channel; sperm associated 3 antibody; CatSper3 antibody; CTSR3_HUMAN antibody; One-repeat calcium channel-like protein antibody; putative ion channel CatSper3 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q86XQ3 Immunogen: Fusion protein of Human CATSPER3 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000 Background: CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CATSPER3 Research Areas: Developmental biology;Metabolism;Signal transduction