CTSB Antibody

Size : 50 µL Clone Number: Aliases: Amyloid precursor protein secretase antibody; APP secretase antibody; APPS antibody; CATB_HUMAN antibody; Cathepsin B heavy chain antibody; Cathepsin B1 antibody; CathepsinB antibody; CPSB antibody; CTSB antibody; cysteine protease antibody; OTTHUMP00000116009 antibody; OTTHUMP00000229510 antibody; OTTHUMP00000229511 antibody; OTTHUMP00000229512 antibody; OTTHUMP00000229514 antibody; OTTHUMP00000229515 antibody; OTTHUMP00000229516 antibody; Preprocathepsin B antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P07858 Immunogen: Fusion protein of Human CTSB Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 10000, IHC: 1: 150-1: 500 Background: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTSB Research Areas: Neuroscience?Cancer;Signal transduction