CEP152 Antibody

Size : 100 µL Clone Number: Aliases: Asterless antibody; CE152_HUMAN antibody; Centrosomal protein 152kDa antibody; Centrosomal protein of 152 kDa antibody; Cep152 antibody; FLJ21594 antibody; KIAA0912 antibody; MCPH4 antibody; MCPH9 antibody; Microcephaly primary autosomal recessive 4 antibody; SCKL5 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O94986 Immunogen: Synthesized peptide derived from internal of Human CEP152. Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; IHC: 1: 50-1: 100 Background: Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles. Nagase T., DNA Res. 5: 355-364(1998). The MGC Project Team; Genome Res. 14: 2121-2127(2004). Andersen J.S., Nature 426: 570-574(2003). Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CEP152 Research Areas: Epigenetics and Nuclear Signaling;Cell biology;Tags & Cell Markers