CTSK Antibody

Size : 50 µL Clone Number: Aliases: Cathepsin K antibody; Cathepsin O antibody; Cathepsin O1 antibody; Cathepsin O2 antibody; Cathepsin X antibody; CATK_HUMAN antibody; CTS02 antibody; Ctsk antibody; CTSO antibody; CTSO1 antibody; CTSO2 antibody; MGC23107 antibody; PKND antibody; PYCD antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P43235 Immunogen: Synthetic peptide of Human CTSK Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTSK Research Areas: Neuroscience?Cancer Cardiovascular?Cell biology;Signal transduction