DCTN1 Antibody

Size : 50 µL Clone Number: Aliases: 150 kDa dynein associated polypeptide antibody; 150 kDa dynein-associated polypeptide antibody; DAP 150 antibody; DAP-150 antibody; DAP150 antibody; DCTN 1 antibody; DCTN1 antibody; DCTN1_HUMAN antibody; DP 150 antibody; DP-150 antibody; DP150 antibody; Dynactin 1 (p150 Glued (Drosophila) homolog) antibody; Dynactin 1 (p150 glued homolog Drosophila) antibody; Dynactin 1 antibody; Dynactin subunit 1 antibody; Dynactin1 antibody; HMN7B antibody; p135 antibody; p150 Glued (Drosophila) homolog antibody; p150 glued antibody; p150 glued homolog antibody; p150(GLUED) DROSOPHILA HOMOLOG OF antibody; p150-glued antibody; p150glued antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q14203 Immunogen: Fusion protein of Human DCTN1 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 10000, WB: 1: 200-1: 1000, IHC: 1: 100-1: 300 Background: This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: DCTN1 Research Areas: Neuroscience;Cell biology;Signal transduction