CYP27A1 Antibody

Size : 50 µL Clone Number: Aliases: 12-alpha-triol 27-hydroxylase antibody; 5-beta-cholestane-3-alpha antibody; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 26-hydroxylase antibody; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase antibody; 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase antibody; 7-alpha antibody; Cholestanetriol 26 monooxygenase antibody; CP27 antibody; CP27A_HUMAN antibody; CTX antibody; CYP antibody; CYP27 antibody; CYP27A1 antibody; Cytochrome P 450C27/25 antibody; Cytochrome P-450C27/25 antibody; Cytochrome P450 27 antibody; Cytochrome P450 27 mitochondrial antibody; Cytochrome P450 family 27 subfamily A member 1 antibody; Cytochrome P450 family 27 subfamily A polypeptide 1 antibody; Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1 antibody; mitochondrial antibody; Sterol 26 hydroxylase antibody; Sterol 26 hydroxylase mitochondrial antibody; Sterol 26-hydroxylase antibody; Sterol 27 hydroxylase antibody; Sterol 27-hydroxylase antibody; Vitamin D(3) 25 hydroxylase antibody; Vitamin D(3) 25-hydroxylase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q02318 Immunogen: Fusion protein of Human CYP27A1 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000, IHC: 1: 25-1: 100 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP27A1 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction